Mote in God's eye

What would the "mote in God's eye" mean, I believe it is a sci-fi title.

It is indeed the title of a book by 1974 book by Larry Niven and David Pournelle
en.wikipedia.org/ wiki/The_Mote_In_God%27s_Eye
The mote is a star that appears to be in front of a larger star (the eye) in a nebula that looks like a face.

It's a reference to the King James Version of the Bible - either Matthew 7:3-5 or Luke 6:41.