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The meaning and origin of the expression: Can a leopard change its spots?

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Can a leopard change its spots?

Meaning

Proverbial question, querying the ability of any person or creature to change its innate being.

Origin

From the Bible, Jeremiah 13:23 (King James Version):

Can the Ethiopian change his skin, or the leopard his spots? then may ye also do good, that are accustomed to do evil.